Giacomo Agostini has won the most MotoGP riders’ titles, with 8.
Drivers with multiple titles:
- Giacomo Agostini — 8
- Marc Márquez — 7
- Valentino Rossi — 7
- Mick Doohan — 5
- Eddie Lawson — 4
- Geoff Duke — 4
- John Surtees — 4
- Mike Hailwood — 4
Based on MotoGP champions 1949–2025.